BioProfile® FLEX2

Automated Cell Culture Analyzer with Maintenance-Free Chemistry Sensors

The BioProfile FLEX2 cell culture analyzer combines Nova’s groundbreaking MicroSensorTM Card technology with optical measurement and freezing point osmometry to create an automated and comprehensive cell culture analyzer that eliminates chemistry sensor maintenance, increases analyzer speed, and reduces sample volume. Gluc, Lac, Gln, Glu, NH4+, Na+, K+, Ca++, pH, PCO2, PO2, total cell density, viable cell density, viability, cell diameter, and osmolality are among the 16 cell culture tests available.

Features

  • ModuleAnalysis TimeSample Size

    Gas Module:
    pH, PCO2 , PO2

    		120 sec275 μl
    Chemistry Module:
    Gluc, Lac, Gln, Glu, NH4+, Na+, K+, Ca++    		120 sec135 μl
    Osmometry Module:
    Osmolality    		240 sec145 μl
    Cell Density/Viability Module:
    Total cell density, viability, cell diameter    		240 sec135 μl

FLEX2 Online Autosampler

Online sampling is possible with BioProfile FLEX2. From single-use bench scale bioreactors to large production bioreactors, Nova’s FLEX2 On-Line Autosampler (OLS) allows completely automated sampling from almost all culture systems. FLEX2 with OLS transmits real-time data for automated sampling, analysis, and feedback control of all measured parameters when connected to an OPC-compatible control system. The OLS can link up to ten vessels, and a full bench of ten bioreactors may be set up in under 20 minutes.

FLEX2 and ESM integration with ambr® 250 and ambr 15 cell culture systems

Nova has also linked the FLEX2 analyzer with ambr 15 and 250 microbioreactors to give a fully automated solution. The External Sampling Module (ESM) of FLEX2 automatically transports cell culture samples from ambr® 250 and ambr® 15 microbioreactor systems to FLEX2 for analysis.

Maintenance-free microsensor cards

Nova has also linked the FLEX2 analyzer with ambr 15 and 250 microbioreactors to give a fully automated solution. The External Sampling Module (ESM) of FLEX2 automatically transports cell culture samples from ambr® 250 and ambr® 15 microbioreactor systems to FLEX2 for analysis.

Guaranteed Measurement Accuracy

The RMS from FLEX2 includes smart reagent cartridges that are simple to use and refill.
• RMS records the date and time of cartridge installation, as well as the lot number and expiration date.
• A self-contained trash receptacle within the cartridge minimises direct waste handling and direct interaction with hazardous trypan blue and biological contaminants, maximising analyzer readiness. Other systems can expose operators to considerable waste management risks.

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